The Transderm® Ionto system and the DEP system are FDA cleared powered drug delivery systems that are indicated for the local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections.

In aesthetics, the Transderm has been widely used for facial rejuvenation, wrinkle reduction, fat reduction, and cellulite reduction. Your options for transdermal delivery are virtually limitless – use the professional-grade or prescription product of your choice!


  • Facial Rejuvenation
  • Fine Lines and Wrinkles
  • Hyperpigmentation
  • Lifting and Tightening
  • Skin Texture Enhancement
  • Acne
  • Cellulite
  • Facial Rejuvenation
  • Needle Free Mesotherapy


  • Needle free transdermal delivery
  • Prescription or professional-grade
  • Comfortable treatments
  • Optional microdermabrasion system


Transderm Ionto System – Includes the Ultrapeel Microdermabrasion System

Transderm DEP System – Does not include the Ultrapeel Microdermabrasion System

The Company

The Microdermabrasion system was designed by Mattioli Engineering of Florence, Italy. Based on innovative design and invaluable experience gained over 20 years, the system can offer therapy to achieve smooth, glowing skin for everyone. More recently, Mattioli Engineering has introduced the Transderm Ionto System to the US market. This FDA cleared system is used worldwide as an alternative to injections.

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